A patient must choose to have life-changing surgery.
- Freddie Highmore as Dr. Shaun Murphy
- Nicholas Gonzalez as Dr. Neil Melendez
- Antonia Thomas as Dr. Claire Browne
- Chuku Modu as Dr. Jared Kalu
- Hill Harper as Dr. Marcus Andrews
- Anna Belknap as Cora
- This is the first episode Richard Schiff hasn't been in.